La metformina es un agente oral hipoglucemiante que se utiliza en el tratamiento de la diabetes mellitus tipo 2. Los resultados del UK Prospective Diabetes. ACIDOSIS LACTICA Es una forma de acidosis metabólica caracterizada por los niveles elevados de acido láctico Niveles bajos de bicarbonato sérico. PDF | Introducción La acidosis láctica se diagnostica mediante la acidosis metabólica, que se asocia a una elevada concentración sérica del lactato.

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Si la enfermedad evoluciona sin tratamiento el pacientre sufre un shock y muere. Lactic acidosis induced by metformin: Send this link to let others join your presentation: Comments 0 Please log in to add your comment. We use cookies to help provide and enhance our service and tailor content and ads. Elsevier About ScienceDirect Remote access Shopping cart Contact and support Terms and conditions Privacy policy We use cookies to help provide and enhance our service and tailor content and ads.

Stand out and be remembered with Prezi, the secret weapon of great presenters. Send the link below via email or IM. Previous renal function was normal. However, in some patients, specially those with acidsois, metformin can provoke severe lactic acidosis with high morbimortality.


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Papel del nefrólogo en la acidosis láctica grave por metformina

Lactic acidosis is an uncommon side effect of metformin use, which is more likely to arise in patients with certain predisposing factors. Cochrane Database Syst Rev 4: Reset share links Resets both viewing and editing links coeditors shown below are not affected. Lactic acidosis is a serious complication of metformin therapy and is more frequent in patients with kidney failure and other intercurrent complaints.

We present the case of a patient with hypertension treated with indapamide and captopril and type 2 diabetes mellitus treated with insulin and metformin.

N Engl J Med ; 9: Add a personal note: El tratamiento se basa en el uso de soluciones alcalinizantes para eliminar la fuente de lactato y removerlo de la sangre. Crit Care ;12 6: A firewall is blocking access to Prezi content. Treatment of the lactic acidosis induced by metformin is based on the use of supportive general measures; in severe cases, procedures of extrarrenal purification like hemodialysis or continuous hemodiafiltration have been successfully used.

Combination of intermittent haemodialysis and high-volume continuous haemofiltration for the treatment of severe metformin-induced lactic acidosis. It is very effective and is able to reduce the plasma glucose and HbA 1C.

Papel del nefrólogo en la acidosis láctica grave por metformina

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By continuing you agree to the use of cookies. Endocrinol Nutr ;57 5: Una semana antes de su ingreso tuvo un cuadro sincopal mientras trabajaba en el campo.

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Metformin, sulfonylureas, or other aicdosis drugs and the risk of lactic acidosis or hypoglycemia: Nephrol Dial Transplant ;23 7: Lactic acidosis in metformin therapy.

The management of metformin overdose. Send link to edit together this prezi using Prezi Meeting learn more: Metformin-associated lactic acidosis in type 2 diabetes mellitus: Metformin-associated lactic acidosis in an intensive care unit. Send the link below via email or IM Copy. Reality of severe metformin-induced lactic acidosis in the absence of chronic renal impairment.

Med Intensiva ;31 9: Constrain to simple back and forward steps.